Transcriptomics

Dataset Information

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MiRNAs differentially expressed in MLL-AF9-transduced versus HOXA9/MEIS1-transduced LSK cells


ABSTRACT: HOXA9 and MEIS1 are essential downstream effectors of the MLL-AF9 oncoprotein during leukemia induction. Leukemia derived from MLL-AF9-transduced LSK cells has a more aggressive phenotype than that derived from HOXA9/MEIS1-transduced LSK cells. To determine differential miRNA expression that contributes to increased aggressiveness in MLL-AF9-induced leukemia, miRCURY LNA microRNA Array was performed on LSK cells transduced with MLL-AF9 versus HOXA/MEIS1 oncogenes.

ORGANISM(S): Mus musculus  

SUBMITTER: Jenny Wang  

PROVIDER: E-MTAB-7356 | ArrayExpress | 2019-07-03

REPOSITORIES: ArrayExpress

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