Transcriptomics

Dataset Information

32

RNA-seq analysis of C. elegans mina-1 mutants


ABSTRACT: Comparative transcriptomics study between C. elegans wild-type N2 and mina-1 mutants.

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Caenorhabditis elegans  

SUBMITTER: Michael O Hengartner   Kapil Dev Singh  

PROVIDER: E-MTAB-7389 | ArrayExpress | 2019-02-13

SECONDARY ACCESSION(S): ERP111974

REPOSITORIES: ArrayExpress, ENA

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Publications


Post-transcriptional control of mRNAs by RNA-binding proteins (RBPs) has a prominent role in the regulation of gene expression. RBPs interact with mRNAs to control their biogenesis, splicing, transport, localization, translation, and stability. Defects in such regulation can lead to a wide range of human diseases from neurological disorders to cancer. Many RBPs are conserved between Caenorhabditis elegans and humans, and several are known to regulate apoptosis in the adult C. elegans germ line.  ...[more]

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