Transcriptomics

Dataset Information

0

3prime RNA-seq of murine SCLC cell line modified with CRISPR-activation of Myc, Mycl or Mycn


ABSTRACT: In cells derived from a genetically engineered Rb1 and Trp53 loss mouse model of SCLC (RP) expression of one of the three MYC family members induced from the endogenous locus using CRISPR activation. Cells were first stably transfected with the lenti-MS2-p65-HSF1 activator plasmid. Respective sgRNAs targeting either Myc, Mycl or MYCN were then cloned into the lentiSAMv2 system and transfected separately into the MS2-p65-HSF1 cells using lentiviral delivery.

INSTRUMENT(S): Illumina HiSeq 4000

ORGANISM(S): Mus musculus  

SUBMITTER: Martin L Sos   Johannes Braegelmann  

PROVIDER: E-MTAB-7411 | ArrayExpress | 2019-07-09

SECONDARY ACCESSION(S): ERP112223

REPOSITORIES: ArrayExpress, ENA

Similar Datasets

2018-05-01 | E-MTAB-6287 | ArrayExpress
2016-04-13 | E-GEOD-80207 | ArrayExpress
2019-01-12 | E-MTAB-7251 | ArrayExpress
2019-06-20 | E-MTAB-8040 | ArrayExpress
2013-02-10 | E-GEOD-44094 | ArrayExpress
2016-10-28 | E-MTAB-5150 | ArrayExpress
2019-04-05 | E-MTAB-7784 | ArrayExpress
| GSE90716 | GEO
2014-03-18 | E-GEOD-55944 | ArrayExpress
| GSE87257 | GEO