Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 4000
ORGANISM(S): Mus musculus
SUBMITTER: Shawez Khan
PROVIDER: E-MTAB-8077 | ArrayExpress | 2020-02-13
SECONDARY ACCESSION(S): ERP115884
REPOSITORIES: ArrayExpress, ENA
Kalucka Joanna J de Rooij Laura P M H LPMH Goveia Jermaine J Rohlenova Katerina K Dumas Sébastien J SJ Meta Elda E Conchinha Nadine V NV Taverna Federico F Teuwen Laure-Anne LA Veys Koen K García-Caballero Melissa M Khan Shawez S Geldhof Vincent V Sokol Liliana L Chen Rongyuan R Treps Lucas L Borri Mila M de Zeeuw Pauline P Dubois Charlotte C Karakach Tobias K TK Falkenberg Kim D KD Parys Magdalena M Yin Xiangke X Vinckier Stefan S Du Yuxiang Y Fenton Robert A RA Schoonjans Luc L Dewerchin Mieke M Eelen Guy G Thienpont Bernard B Lin Lin L Bolund Lars L Li Xuri X Luo Yonglun Y Carmeliet Peter P
Cell 20200213 4
The heterogeneity of endothelial cells (ECs) across tissues remains incompletely inventoried. We constructed an atlas of >32,000 single-EC transcriptomes from 11 mouse tissues and identified 78 EC subclusters, including Aqp7+ intestinal capillaries and angiogenic ECs in healthy tissues. ECs from brain/testis, liver/spleen, small intestine/colon, and skeletal muscle/heart pairwise expressed partially overlapping marker genes. Arterial, venous, and lymphatic ECs shared more markers in more tissues ...[more]