Transcriptomics

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Deletion of LOX-1 has protective effects on ischemic brain damage in the genetic background of stroke-prone spontaneously hypertensive rat


ABSTRACT: To explore the impact of oxidized low density lipoprotein receptor 1 (Olr1 aka LOX-1) gene on stroke, we newly generate a LOX-1 deficient strain of the genetic background of stroke-prone spontaneously hypertensive rat (SHRSP). We explored circulatory miRNAs as diagnostic biomarkers for cerebral ischemic injury by microarray analysis in related rat strains.

ORGANISM(S): Rattus norvegicus  

SUBMITTER: Norihiro Kato   Fumihiko Takeuchi  

PROVIDER: E-MTAB-8388 | ArrayExpress | 2020-05-19

REPOSITORIES: ArrayExpress

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