Transcriptomics

Dataset Information

0

Single-cell RNA-sequencing of mouse thymic epithelial cells across the first year of life


ABSTRACT: The thymus shapes the T cell receptor repertoire, and is one of the first organs to rapidly age, with gross changes in cellularity and architecture. To resolve the nature of these changes we used SMART-Seq2 on FACS purified thymic epithelial cells (TEC) across the first year of mouse life. We sorted 4 TEC populations in each of 5 mice at each age (1 week, 4 weeks, 16 weeks, 32 weeks and 52 weeks old).

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus  

SUBMITTER: Mike Morgan   Jeanette Baran-Gale  

PROVIDER: E-MTAB-8560 | ArrayExpress | 2020-09-14

SECONDARY ACCESSION(S): ERP119415

REPOSITORIES: ArrayExpress, ENA

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