Transcriptomics

Dataset Information

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Organotypic human bronchial epithelial cultures (MucilAir) exposed to aqueous aerosol extracts of the 3R4F cigarette smoke and a novel tobacco product vapor


ABSTRACT: The current study was performed for analysis of the biological effects of vapor from novel tobacco vapor product in comparison with 3R4F cigarette smoke. This study was performed using a three-dimensional culture system composed of an air-liquid interface culture of primary normal human bronchial epithelial cells (MucilAir). The MucilAir tissues were subjected to 17 days of exposure to the aqueous extract of novel tobacco product vapor or 3R4F cigarette smoke. The number of differentially expressed genes increased in MucilAir tissues exposed to aqueous extract of each test product dependent on exposure duration. The number of differentially expressed genes was lower in the tissues exposed to aqueous extract of novel tobacco product vapor compared to the tissues exposed to aqueous extract of 3R4F cigarette smoke.

ORGANISM(S): Homo sapiens  

DISEASE(S): Normal

SUBMITTER: Shinkichi Ishikawa  

PROVIDER: E-MTAB-8920 | ArrayExpress | 2020-04-15

REPOSITORIES: ArrayExpress

Dataset's files

Source:
Action DRS
E-MTAB-8920.idf.txt Idf
E-MTAB-8920.idf.txt_original Idf
E-MTAB-8920.raw.1.zip Raw
E-MTAB-8920.raw.2.zip Raw
E-MTAB-8920.raw.3.zip Raw
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