Transcriptomics

Dataset Information

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Glucocorticoid and androgen receptor profiling (ChIP-seq) in U2OS-GR and U2OS-AR cells upon hormone treatment


ABSTRACT: We performed ChIP-seq targeting the glucocorticoid receptor (GR) in the U2OS-GR cell line and the androgen receptor (AR) in the U2OS-AR cell line. The cell lines are derived from U2OS ATTC:HTB-96 and stably transfected with an expression construct for either rat GR or human AR, respectively. The U2OS-GR cells were treated with dexamethasone (1 µM) for 90 minutes. The U2OS-AR cells were treated with R1881 (5 nM) for 4 hours.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Homo sapiens  

DISEASE(S): Osteosarcoma

SUBMITTER: Sebastiaan H Meijsing   Melissa Bothe  

PROVIDER: E-MTAB-9616 | ArrayExpress | 2021-03-09

SECONDARY ACCESSION(S): ERP124250

REPOSITORIES: ArrayExpress, ENA

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