Transcriptomics

Dataset Information

25

Transcription profiling by array of formalin-fixed and paraffin-embedded (FFPE) tumor samples.


ABSTRACT: Transcription profiling by array of formalin-fixed and paraffin-embedded (FFPE) tumor samples.

ORGANISM(S): Homo Sapiens

DISEASE(S): Colorectal Adenocarcinoma

SUBMITTER: Mauro Delorenzi  

PROVIDER: E-MTAB-990 | ArrayExpress | 2013-06-21

REPOSITORIES: ArrayExpress

Dataset's files

Source:
Action DRS
E-MTAB-990.README.txt Txt
E-MTAB-990.idf.txt Idf
E-MTAB-990.processed.2.zip Processed
E-MTAB-990.raw.1.zip Raw
E-MTAB-990.raw.10.zip Raw
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Publications


The recognition that colorectal cancer (CRC) is a heterogeneous disease in terms of clinical behaviour and response to therapy translates into an urgent need for robust molecular disease subclassifiers that can explain this heterogeneity beyond current parameters (MSI, KRAS, BRAF). Attempts to fill this gap are emerging. The Cancer Genome Atlas (TGCA) reported two main CRC groups, based on the incidence and spectrum of mutated genes, and another paper reported an EMT expression signature defined  ...[more]

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