Transcriptomics

Dataset Information

6

Comparative genomic hybridization of forty clinical isolates from twelve common serovars within Salmonella enterica subspecies I (sspI) to identify the conserved gene pool present


ABSTRACT: We have performed microarray hybridization studies on forty clinical isolates from twelve common serovars within Salmonella enterica subspecies I (sspI) to identify the conserved gene pool present.

SUBMITTER: Martin J. Woodward  Muna F. Anjum  Maria Fookes  Chris Marooney  Gordon Dougan  Matloob Qureshi  Stephen Baker  Al Ivens 

PROVIDER: E-SGRP-1 | ArrayExpress | 2005-12-06

REPOSITORIES: ArrayExpress

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Publications

Identification of core and variable components of the Salmonella enterica subspecies I genome by microarray.

Anjum Muna F MF   Marooney Chris C   Fookes Maria M   Baker Stephen S   Dougan Gordon G   Ivens Al A   Woodward Martin J MJ  

Infection and immunity 20051201 12


We have performed microarray hybridization studies on 40 clinical isolates from 12 common serovars within Salmonella enterica subspecies I to identify the conserved chromosomal gene pool. We were able to separate the core invariant portion of the genome by a novel mathematical approach using a decision tree based on genes ranked by increasing variance. All genes within the core component were confirmed using available sequence and microarray information for S. enterica subspecies I strains. The  ...[more]

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