Dataset Information


Transcription profiling of human placenta vs a placenta reference

ABSTRACT: Total RNA was isolated from all the placental tissues using Trizol, and mRNA was isolated using FastTrack Kit. We used a placenta reference as a standard for all these array hybridizations. The placenta reference is a mixture of placenta mRNA with CRG.

ORGANISM(S): Homo sapiens  

SUBMITTER: Ruchira Sood   Janos Demeter  

PROVIDER: E-SMDB-985 | ArrayExpress | 2006-09-15


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Gene expression patterns in human placenta.

Sood Ruchira R   Zehnder James L JL   Druzin Maurice L ML   Brown Patrick O PO  

Proceedings of the National Academy of Sciences of the United States of America 20060327 14

The placenta is the principal metabolic, respiratory, excretory, and endocrine organ for the first 9 months of fetal life. Its role in fetal and maternal physiology is remarkably diverse. Because of the central role that the placenta has in fetal and maternal physiology and development, the possibility that variation in placental gene expression patterns might be linked to important abnormalities in maternal or fetal health, or even variations in later life, warrants investigation. As an initial  ...[more]

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