Transcriptomics

Dataset Information

7

Transcription profiling of matching human primary head and neck squamous cell carcinomas and cervical lymph node metastases.


ABSTRACT: An experiment was performed to investigate the perservation of gene expression upon metastasis of primary head and neck squamous cell carcinomas to the cervical lymph node.

ORGANISM(S): Homo sapiens  

DISEASE(S): Oropharynx Squamous-cell Carcinoma In Diseaselocation Oropharynx Has Diseasestaging Lymph Node Negative (n0),Oropharynx Squamous-cell Carcinoma In Diseaselocation Oropharynx Has Diseasestaging Lymph Node Metastasis (n+),Oral Cavity Squamous-cell Carcinoma In Diseaselocation Oral Cavity Has Diseasestaging Lymph Node Metastasis (n+),Head And Neck Squamous Cell Carcinoma,Oral Cavity Squamous-cell Carcinoma In Diseaselocation Oral Cavity Has Diseasestaging Lymph Node Negative (n0)

SUBMITTER: Paul Roepman  

PROVIDER: E-TABM-114 | ArrayExpress | 2006-10-23

REPOSITORIES: ArrayExpress

altmetric image

Publications

Maintenance of head and neck tumor gene expression profiles upon lymph node metastasis.

Roepman Paul P   de Jager Alike A   Groot Koerkamp Marian J A MJ   Kummer J Alain JA   Slootweg Piet J PJ   Holstege Frank C P FC  

Cancer research 20061201 23


Spread of cancer and development of solid metastases at distant sites is the main cause of cancer-related deaths. To understand and treat metastases, it is important to determine at which stages the most pivotal steps for development of metastases occur. In head and neck squamous cell carcinoma (HNSCC), metastasis nearly always occurs first in local lymph nodes before development of distant metastasis. Here, we have investigated gene expression patterns in HNSCC lymph node metastases using DNA m  ...[more]

Similar Datasets

2007-11-02 | E-TABM-152 | ArrayExpress
2007-06-01 | E-MEXP-745 | ArrayExpress
2007-06-01 | E-MEXP-753 | ArrayExpress
2015-10-22 | E-MEXP-1179 | ExpressionAtlas
2009-10-01 | E-MEXP-2081 | ArrayExpress
2016-01-05 | E-TABM-82 | ExpressionAtlas
2015-12-04 | E-TABM-142 | ExpressionAtlas
2011-01-12 | E-TABM-1209 | ArrayExpress
2010-12-18 | E-MTAB-192 | ArrayExpress
2007-04-01 | E-MEXP-802 | ArrayExpress