Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: MODEL2101150001PRJNA146093PRJNA174603
ORGANISM(S): Mus musculus
SUBMITTER: Richard Jenner
PROVIDER: E-TABM-1187 | ArrayExpress | 2012-10-29
REPOSITORIES: ArrayExpress
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E-TABM-1187.README.txt | Txt | |||
E-TABM-1187.idf.txt | Idf | |||
E-TABM-1187.processed.1.zip | Processed | |||
E-TABM-1187.processed.2.zip | Processed | |||
E-TABM-1187.raw.1.zip | Raw |
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Gökmen M Refik MR Dong Rong R Kanhere Aditi A Powell Nick N Perucha Esperanza E Jackson Ian I Howard Jane K JK Hernandez-Fuentes Maria M Jenner Richard G RG Lord Graham M GM
Journal of immunology (Baltimore, Md. : 1950) 20131118 12
The complex relationship between Th1 and Th17 cells is incompletely understood. The transcription factor T-bet is best known as the master regulator of Th1 lineage commitment. However, attention is now focused on the repression of alternate T cell subsets mediated by T-bet, particularly the Th17 lineage. It has recently been suggested that pathogenic Th17 cells express T-bet and are dependent on IL-23. However, T-bet has previously been shown to be a negative regulator of Th17 cells. We have tak ...[more]