Transcriptomics

Dataset Information

2

Hepatic transcriptomic analysis of inter-family variability in flesh n-3 long-chain polyunsaturated fatty acid content in Atlantic salmon


ABSTRACT: Liver transcriptomes of Atlantic salmon families with contrasting flesh n-3 LC-PUFA profiles, and all fed the same 100% vegetable oil replacement diet, were compared by microarray analysis (Agilent oligoarray platform). The objective was to identify gene pathways and molecular mechanisms which might explain differences in flesh n-3 LC-PUFA content, independent of total lipid deposition, when salmon families are fed the same LC-PUFA deficient diet. A factorial design was chosen in which families containing higher and lower n-3 LC-PUFA relative levels were compared at similar total lipid percentages in flesh.

ORGANISM(S): Salmo salar  

SUBMITTER: John Taggart  

PROVIDER: E-TABM-1204 | ArrayExpress | 2011-09-15

REPOSITORIES: ArrayExpress

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Publications

Hepatic transcriptome analysis of inter-family variability in flesh n-3 long-chain polyunsaturated fatty acid content in Atlantic salmon.

Morais Sofia S   Taggart John B JB   Guy Derrick R DR   Bell J Gordon JG   Tocher Douglas R DR  

BMC genomics 20120820


BACKGROUND: Genetic selection of Atlantic salmon families better adapted to alternative feed formulations containing high levels of vegetable ingredients has been suggested to ensure sustainable growth of aquaculture. The present study aimed to identify molecular pathways that could underlie phenotypic differences in flesh n-3 long-chain polyunsaturated fatty acid (LC-PUFA) levels when fish are fed vegetable oil diets. Liver transcriptome was analyzed and compared in four families presenting hig  ...[more]

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