Dataset Information

23

Transcription profiling of fat biopsies from normoglycaemic twins (MolPAGE study)


ABSTRACT: Fat biopsies from normoglycaemic twins were analysed on Affymetrix arrays

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Homo sapiens  

SUBMITTER: Maria Krestyaninova   

PROVIDER: E-TABM-325 | ArrayExpress| 2014-08-06

REPOSITORIES: ArrayExpress

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Publications


Metabolic Syndrome (MetS) is highly prevalent and has considerable public health impact, but its underlying genetic factors remain elusive. To identify gene networks involved in MetS, we conducted whole-genome expression and genotype profiling on abdominal (ABD) and gluteal (GLU) adipose tissue, and whole blood (WB), from 29 MetS cases and 44 controls. Co-expression network analysis for each tissue independently identified nine, six, and zero MetS-associated modules of coexpressed genes in ABD,  ...[more]

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