Transcriptomics

Dataset Information

8

Transcription profiling of Porphyromonas gingivalis W50 cells grown in biofilm or planktonically


ABSTRACT: Transcriptomic profiling of P. gingivalis W50 biofilm grown cells to that of planktonic cells.

ORGANISM(S): Porphyromonas gingivalis  

SUBMITTER: Alvin Lo  

PROVIDER: E-TABM-467 | ArrayExpress | 2009-01-31

REPOSITORIES: ArrayExpress

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Publications

Comparative transcriptomic analysis of Porphyromonas gingivalis biofilm and planktonic cells.

Lo Alvin W AW   Seers Christine A CA   Boyce John D JD   Dashper Stuart G SG   Slakeski Nada N   Lissel J Patricia JP   Reynolds Eric C EC  

BMC microbiology 20090129


BACKGROUND: Porphyromonas gingivalis in subgingival dental plaque, as part of a mature biofilm, has been strongly implicated in the onset and progression of chronic periodontitis. In this study using DNA microarray we compared the global gene expression of a P. gingivalis biofilm with that of its planktonic counterpart grown in the same continuous culture. RESULTS: Approximately 18% (377 genes, at 1.5 fold or more, P-value < 0.01) of the P. gingivalis genome was differentially expressed when the  ...[more]

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