Transcriptomics

Dataset Information

4

ChIP-chip of Drosophila Polycomb group proteins Pho and dSfmbt (PhoRC) in embryos and larvae


ABSTRACT: Analysis of binding profile of the Polycomb group proteins Pho and dSfmbt (PhoRC complex) in Drosophila melanogster at two developmental stages (embryos and larvae).

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Drosophila Melanogaster

TISSUE(S): Wing/haltere/third Leg, Whole Organism

SUBMITTER: Charles Girardot  

PROVIDER: E-TABM-525 | ArrayExpress | 2008-11-06

REPOSITORIES: ArrayExpress

Dataset's files

Source:
Action DRS
E-TABM-525.README.txt Txt
E-TABM-525.eSet.r Other
E-TABM-525.idf.txt Idf
E-TABM-525.idf.txt_original Idf
E-TABM-525.raw.1.zip Raw
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Publications

Dynamic regulation by polycomb group protein complexes controls pattern formation and the cell cycle in Drosophila.

Oktaba Katarzyna K   Gutiérrez Luis L   Gagneur Julien J   Girardot Charles C   Sengupta Aditya K AK   Furlong Eileen E M EE   Müller Jürg J  

Developmental cell 20081106 6


Polycomb group (PcG) proteins form conserved regulatory complexes that modify chromatin to repress transcription. Here, we report genome-wide binding profiles of PhoRC, the Drosophila PcG protein complex containing the DNA-binding factor Pho/dYY1 and dSfmbt. PhoRC constitutively occupies short Polycomb response elements (PREs) of a large set of developmental regulator genes in both embryos and larvae. The majority of these PREs are co-occupied by the PcG complexes PRC1 and PRC2. Analysis of PcG  ...[more]

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