Transcriptomics

Dataset Information

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Transcription profiling of Enterococcus faecalis V583 in response to NaCl


ABSTRACT: The effects of NaCl on transcriptional events were studied by means of genome wide microarrays in Enterococcus faecalis V583. Transcriptional profiles were obtained through time series experiments over periods of 60min.

ORGANISM(S): Enterococcus faecalis  

SUBMITTER: Margrete Solheim   

PROVIDER: E-TABM-904 | ArrayExpress | 2014-05-02

REPOSITORIES: ArrayExpress

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Publications

Transcriptomic and functional analysis of NaCl-induced stress in Enterococcus faecalis.

Solheim Margrete M   La Rosa Sabina Leanti SL   Mathisen Thomas T   Snipen Lars G LG   Nes Ingolf F IF   Brede Dag Anders DA  

PloS one 20140422 4


The robust physiology of Enterococcus faecalis facilitates tolerance to various stresses. We here report the transcriptional response of E. faecalis V583 to growth in the presence of 6.5% NaCl. Among the early responses observed was an immediate down-regulation of mscL, accompanied by an up-regulation of genes predicted to be involved in uptake of extracellular potassium and glycine betaine. The high NaCl concentration also induced expression of chaperons and cell envelope related traits, such a  ...[more]

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