Transcriptomics

Dataset Information

5

Transcription profiling by array of brains from Apis mellifera mellifera and Apis mellifera ligustica honey bees of different ages


ABSTRACT: Expression profiling of honey bees brains as a function of genotype ( Apis mellifera mellifera/Apis mellifera ligustica) and age

INSTRUMENT(S): Axon GenePix 4000B scanning hardware

ORGANISM(S): Apis mellifera  

SUBMITTER: Cedric Alaux  

PROVIDER: E-TABM-952 | ArrayExpress | 2010-12-31

REPOSITORIES: ArrayExpress

Dataset's files

Source:
Action DRS
E-TABM-952.README.txt Txt
E-TABM-952.eSet.r Other
E-TABM-952.idf.txt Idf
E-TABM-952.raw.1.zip Raw
E-TABM-952.raw.2.zip Raw
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Publications

New meta-analysis tools reveal common transcriptional regulatory basis for multiple determinants of behavior.

Ament Seth A SA   Blatti Charles A CA   Alaux Cedric C   Wheeler Marsha M MM   Toth Amy L AL   Le Conte Yves Y   Hunt Greg J GJ   Guzmán-Novoa Ernesto E   Degrandi-Hoffman Gloria G   Uribe-Rubio Jose Luis JL   Amdam Gro V GV   Page Robert E RE   Rodriguez-Zas Sandra L SL   Robinson Gene E GE   Sinha Saurabh S  

Proceedings of the National Academy of Sciences of the United States of America 20120612 26


A fundamental problem in meta-analysis is how to systematically combine information from multiple statistical tests to rigorously evaluate a single overarching hypothesis. This problem occurs in systems biology when attempting to map genomic attributes to complex phenotypes such as behavior. Behavior and other complex phenotypes are influenced by intrinsic and environmental determinants that act on the transcriptome, but little is known about how these determinants interact at the molecular leve  ...[more]

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