Transcriptomics

Dataset Information

33

Transcription profiling of heart during hypoxia of the Fawn Hooded Hypertensive (FHH) rat and FHH12BN consomic rat


ABSTRACT: Examination of gene expression changes during hypoxia of the Fawn Hooded Hypertensive (FHH) rat and FHH12BN consomic rat. FHH12BN rats are derived from introgression of chromosome 12 and from the Brown Norway (BN) rat into the FHH genetic background.

ORGANISM(S): Rattus norvegicus  

SUBMITTER: Norman H. Lee  Hongying Wang  Joseph White  Anne E. Kwitek         

PROVIDER: E-TIGR-111 | ArrayExpress| 2014-06-04

REPOSITORIES: ArrayExpress

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Cardiovascular disorders are influenced by genetic and environmental factors. The TIGR rodent expression web-based resource (TREX) contains over 2,200 microarray hybridizations, involving over 800 animals from 18 different rat strains. These strains comprise genetically diverse parental animals and a panel of chromosomal substitution strains derived by introgressing individual chromosomes from normotensive Brown Norway (BN/NHsdMcwi) rats into the background of Dahl salt sensitive (SS/JrHsdMcwi)  ...[more]

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