E-GEOD-15653
Ontology highlight
ABSTRACT:
DISEASE(S): Type Ii Diabetes Mellitus,Normal
PROVIDER: E-GEOD-15653 | ExpressionAtlas | 2025-01-24
REPOSITORIES: ExpressionAtlas
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| E-GEOD-15653-analysis-methods.tsv | Tabular | |||
| E-GEOD-15653-atlasExperimentSummary.Rdata | Rdata | |||
| E-GEOD-15653-configuration.xml | Xml | |||
| E-GEOD-15653-percentile-ranks.tsv | Tabular | |||
| E-GEOD-15653.condensed-sdrf.tsv | Tabular |
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2009-06-01 | E-GEOD-15653 | biostudies-arrayexpress
Project description:Hepatic lipid accumulation is an important complication of obesity linked to risk for type 2 diabetes. To identify novel transcriptional changes in human liver which could contribute to hepatic lipid accumulation and associated insulin resistance and type 2 diabetes (DM2), we evaluated gene expression and gene set enrichment in surgical liver biopsies from 13 obese (9 with DM2) and 5 control subjects, obtained in the fasting state at the time of elective abdominal surgery for obesity or cholecystectomy. RNA was isolated for cRNA preparation and hybridized to Affymetrix U133A microarrays.
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