Project description:Exon array profiling of human primary tumor tissue samples including breast, colon and NSCLC. This dataset includes expression profiles of 153 human primary tumors that were acquired from different commerical vendors and characterized as having >60% tumor content.
Project description:Genome wide DNA methylation profiling of Neurons derived from human induced pluripotent stem cells (iCell Neurons) at different time points were abtained by the Infinium HumanMethylation450 BeadChip (450K array) Kit (WG-314-1002), which interrogates >480,000 CpG sites in the human genome.In total, 36 samples were profiled using the 450K arrays.
Project description:Genome-wide DNA methylation and trancription profiling of different subtypes in GBM (TCGA) and glioma stem cells (GSCs) were carried out using Illumina BeadChip HumanMethylation 450K array (450K array) to analyse over 485K CpG sites accross each samples. 450K array data for 94 GBM samples comprising 4 different subtypes i.e. Proneural (PN), Mesenchymal (MES), Classical (CL) and Neural (N) were used for GBM analysis. Similarly, 450K array for 23 GSCs and 1NHA, RNA seq for 29 GSCs and affimetrix microarray gene expression array for 12 GSCs were used for GBM data analyses.
Project description:Genome wide DNA methylation profiling of four control and cancer cell lines where apoptosis was induced using BH3 mimetics. The Illumina Human MethylationEPIC methylation profiling array was used to obtain DNA methylation profiles across approximately 850,000 CpGs. 8 samples were from treated cells harvested at two different time points representing early and late apoptotic stages, and 4 samples were controls combined from the two timepoints. 4 additional samples was left over DNA from the Nalm6 cell line ran on the array to fill up the bead chips. Data analysis will be presented in the manuscript "HPV-induced host epigenetic reprogramming is lost upon progression to high-grade cervical intraepithelial neoplasia" accepted for publication in the International Journal for Cancer.