Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-GEOD-2116

ABSTRACT: Transcription profiling of rat left ventricular samples from 12-, 16- and 20-month old spontaneously hypertensive rats (SHRs) compared with age-matched Wistar-Kyoto (WKY) rats as controls

OTHER RELATED OMICS DATASETS IN: PRJNA91775

DISEASE(S): Hypertension,Normal

PROVIDER: E-GEOD-2116 | ExpressionAtlas | 2014-08-15

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-GEOD-2116-analysis-methods.tsv	Tabular
	E-GEOD-2116-atlasExperimentSummary.Rdata	Rdata
	E-GEOD-2116-configuration.xml	Xml
	E-GEOD-2116-percentile-ranks.tsv	Tabular
	E-GEOD-2116.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 93

Similar Datasets

SHR-WKY

Project description:Left ventricular gene expression profiles from 12-, 16- and 20-months old spontaneously hypertensive rats (SHRs) were compared with left ventricular profiles seen in age-matched Wistar-Kyoto (WKY) rats by screening Affymetrix U34A arrays (there are 4 samples in each timepoint except 3 samples of 20-months old WKYs). Keywords: time-course

2005-07-01 | GSE2116 | GEO

Transcription profiling of rat left ventricular samples from 12-, 16- and 20-month old spontaneously hypertensive rats (SHRs) compared with age-matched Wistar-Kyoto (WKY) rats as controls

Project description:Left ventricular gene expression profiles from 12-, 16- and 20-months old spontaneously hypertensive rats (SHRs) were compared with left ventricular profiles seen in age-matched Wistar-Kyoto (WKY) rats [control rats] by screening Affymetrix U34A arrays (there are 4 samples in each timepoint except 3 samples of 20-months old WKYs).

2007-09-20 | E-GEOD-2116 | biostudies-arrayexpress

Transcription profiling of feft ventricle in three genetic rat models of hypertension

Project description:Left ventricle gene expression was analyzed in three models of hypertension in order to clarify the molecular mechanisms associated with left ventricular hypertrophy. Transgenic heterozygous TGR(mRen2)27 rats, overexpressing the mouse renin gene, and their littermate negative controls, spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY), and Lyon hypertensive rats (LH) and their normotensive controls (LL) were included in the study.

2006-08-31 | E-MEXP-357 | biostudies-arrayexpress

Transcription profiling of rat resistance artery in 2 models of hypertension

Project description:We investigated morphometric structure and gene expression by microarray analysis in a small diameter artery, branch of the saphenous artery (a resistance artery), in representative models of renin-angiotensin system (RAS)-dependent and glucocorticoid hypertension, using the spontaneously hypertensive rat (SHR) and adrenocorticotropic hormone (ACTH)-induced hypertensive rat, respectively. Sixteen-week-old male Wistar-Kyoto (WKY) and age-matched spontaneously hypertensive rats (SHR) were used. Experiment Overall Design: There were 3 experimental groups: Group 1: 16-week male Wistar-Kyoto rats; Group 2: 16-week male Wistar-Kyoto rats treated with ACTH (0.1mg/kg/day) subcutaneously, for 4 weeks prior to sampling (i.e. during weeks 12-16 of life) ; Group3: 16-week male SHR (spontaneously hypertensive) rats. There were 3 replicate hybridizations in each experimental group. Due to the low yield of total RNA obtained from the arterial sections, each replicate was composed of RNA pooled from 2-3 different rats.

2008-06-15 | E-GEOD-8051 | biostudies-arrayexpress

Gene expression in a resistance artery in 2 models of hypertension in the rat

2007-11-28 | GSE8051 | GEO

Integrated analysis of miRNA-mRNA interactions reveals novel target pathways in hypertension-induced cardiac remodeling (mRNA-seq dataset)

Project description:The goals of the study are to compare differently expressed genes in heart tissues of hypertensive rats (spontaneously Hypertension Rats, SHR) with age-matched control rats (wistar Rats, WKY), identify new targets to reverse hypertension induced cardiac remodeling and idetify the targets of Traditional Chinese Medicine QDG.

2020-01-31 | GSE144548 | GEO

Glucagon-like peptide-1 suppresses sympathetic activation via peripheral chemosensory inhibition

Project description:In order to investigate the molecular basis of carotid body chemoreceptor sensitisation in the Spontaneously Hypertensive Rat (SHR) we have sequenced the transcriptomes of bilateral carotid body samples from aged-matched, male SHR and control Wistar-Kyoto rats.

2022-01-11 | GSE178504 | GEO

SHR and WKY rat adrenal glands

Project description:We measured gene expression in the adrenal glands of the Spontaneously Hypertensive Rat (SHR) and Wistar-Kyoto rat (WKY) using Affymetrix RG-U34A GeneChips. All rats were aged-matched at 4-weeks. The rats were obtained from the colonies at the Univeristy of California San Diego, La Jolla, CA. Keywords: other

2004-11-02 | GSE1675 | GEO

Multi-organ Gene Expression Dynamics and Network Modeling Reveals Sex-specific Shifts in Regulatory Control during the Development of Hypertension

Project description:In this study we performed high throughput microfluidic qPCR using BioMark on RNA extracted from 5 organs (adrenal gland, kidney, liver, lung, and spleen) at 5 different time points throughout the development of hypertension (8, 10, 12, 16, and 24 weeks) in Spontaneously Hypertensive Rats (SHR) as compared to Wistar-Kyoto (WKY) control in female subjects (n=3).

2024-10-24 | GSE227753 | GEO

Transcription profiling of rat adrenal glands from spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto animals

2007-11-01 | E-GEOD-1675 | biostudies-arrayexpress