Dataset Information


RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines

ABSTRACT: This SuperSeries is composed of the following subset Series: GSE30567: ENCODE Cold Spring Harbor Labs Long RNA-seq (hg19) GSE32931: ENCODE Cold Spring Harbor Labs Long RNA-seq (hg18) For data usage terms and conditions, please refer to and Refer to individual Series


ORGANISM(S): Homo sapiens  

PROVIDER: E-GEOD-26284 | ExpressionAtlas | 2015-01-29

REPOSITORIES: ExpressionAtlas

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Many animal species use a chromosome-based mechanism of sex determination, which has led to the coordinate evolution of dosage-compensation systems. Dosage compensation not only corrects the imbalance in the number of X chromosomes between the sexes but also is hypothesized to correct dosage imbalance within cells that is due to monoallelic X-linked expression and biallelic autosomal expression, by upregulating X-linked genes twofold (termed 'Ohno's hypothesis'). Although this hypothesis is well  ...[more]

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