Project description:Quantitative protein profiling of rat liver focused on drug metabolizing enzymes. FFEP and FrFr rat liver tissues applied to the proteomic analysis. Samples were digested by trypsin and labeled with mTRAQ reagent. Tryptic peptides were analyzed by nLC-Orbitrap in DDA mode. MS data were searched against UniProt using Mascot.

2022-07-18 | PXD027375 | JPOST Repository

High resolution methylome map of rat reveals role of intragenic DNA methylation in identifying coding region and alternative splice site.

Project description:We report the application of next generation sequencing technology for high-throughput profiling of cytosine methylation in adult rat liver tissue. To investigate the role of intragenic methylation, we generated the first high resolution methylation map of rat liver tissue and compared it with the proteome of the same rat tissue.

2011-12-20 | E-GEOD-31571 | biostudies-arrayexpress

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