Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-GEOD-46239

ABSTRACT: Transcription profiling by array of skin biopsies from dermatomyositis patients and healthy controls

DISEASE(S): Dermatomyositis,Normal

PROVIDER: E-GEOD-46239 | ExpressionAtlas | 2025-01-24

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-GEOD-46239-analysis-methods.tsv	Tabular
	E-GEOD-46239-atlasExperimentSummary.Rdata	Rdata
	E-GEOD-46239-configuration.xml	Xml
	E-GEOD-46239-percentile-ranks.tsv	Tabular
	E-GEOD-46239.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 49

Similar Datasets

Human Alopecia Areata Skin Biopsy Samples

Project description:Gene expression profiling of scalp skin biopsies from patients with alopecia areata or normal healthy controls Scalp skin punch biopsies were taken from the indicated patients and stored in PAXgene tissue containers for shipping to a central location, where the samples were processed

2017-02-09 | GSE68801 | GEO

H3K27Ac modification and gene expression in psoriasis

Project description:Applying ChIP-seq with anti-acetylation of lysine 27 on Histone 3 (H3K27Ac), we report high-throughput profiling of H3K27Ac in human skin biopsies taken from psoriasis patients, both from the lesion and from adjacent non-lesion skin, and from skin biopsies from healthy match volunteers, in term of age, gender, and the biopsies place in the body. From each group we had 4 samples. On three samples of each group we performed mRNA array. There is a clearly different H3K27 acetylation patterns in psoriatic skin compared to uninvolved or healthy volunteer skin. in many of the most over express genes in psoriasis lesion, there is enrichment of H3K27Ac. However, loss of acetylation on H3K27 is not part of the biochemical mechanism by which gene expression is decreased in psoriatic skin. Finally, we show Many of the over express genes in psoriasis lesion, that also were enriched with H3K27Ac harbor a putative GRHL transcription factor binding site.

2021-01-01 | GSE160932 | GEO

HDMECs isolated from skin biopsies of patients with DFUs and healthy controls

Project description:Human dermal microvascular endothelial cells (HDMECs) were isolated via the magnetic-activated cell sorting (MACS) method from skin biopsies of patients with DFUs and healthy controls. We then performed gene expression profiling analysis using data obtained from RNA-seq of these cells.

2023-09-30 | GSE219078 | GEO

Cutaneous lupus features specialized stromal niches and altered retroelement expression

Project description:Single-cell RNA and spatial sequencing of lesional and non-lesional cutaneous lupus skin compared to healthy controls. The study includes 12 single-cell samples (cutaneous lupus patients with non-lesional (5) and lesional (4) skin biopsies with healthy controls (3)) and 4 spatial transcriptomics samples (cutaneous lupus patient pre/post-Anifrolumab treatment, 1 additional CLE patient, and 1 healthy control).

2025-04-14 | GSE294296 | GEO

H3K27Ac modification and gene expression in psoriasis

Project description:Applying ChIP-seq with anti-acetylation of lysine 27 on Histone 3 (H3K27Ac), we report high-throughput profiling of H3K27Ac in human skin biopsies taken from psoriasis patients, both from the lesion and from adjacent non-lesion skin, and from skin biopsies from healthy match volunteers, in term of age, gender, and the biopsies place in the body. From each group we had 4 samples. There is a clearly different H3K27 acetylation patterns in psoriatic skin compared to uninvolved or healthy volunteer skin. in many of the most over express genes in psoriasis lesion, there is enrichment of H3K27Ac. However, loss of acetylation on H3K27 is not part of the biochemical mechanism by which gene expression is decreased in psoriatic skin. Finally, we show Many of the over express genes in psoriasis lesion, that also were enriched with H3K27Ac harbor a putative GRHL transcription factor binding site.

2023-07-17 | GSE161076 | GEO

Molecular profile of hidradenitis suppurativa

Project description:Hidradenitis Suppurativa molecular taxonomy and key signaling pathways were studied by whole transcriptome profiling. Dysregulated genes were detected by comparing lesional and non lesional skin obtained from female HS patients and matched healthy controls using the Agilent array platform

2019-09-10 | GSE137141 | GEO

HDMECs isolated from skin biopsies of patients with DFUs and healthy controls

Project description:HDMECs isolated from skin biopsies of patients with DFUs and healthy controls

| PRJNA906996 | ENA

Project description:RNA sequencing of skin biopsies from IgA vasculitis patients and healthy controls

| PRJNA1017657 | ENA

Homo sapiens

Project description:Skin biopsies from atopic eczema and healthy controls

| PRJNA97811 | ENA

Genome-wide reduction in chromatin accessibility and unique transcription factor footprints in endothelial cells and fibroblasts in scleroderma skin

Project description:We assessed genome-wide chromatin accessibility and transcription factor footprinting in endothelial cells and fibroblasts isolated from skin biopsies from healthy subjects and diffuse cutaneous scleroderma patients.

2022-09-02 | GSE163199 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data