Project description:This SuperSeries is composed of the following subset Series:; GSE13136: Identification of candidate neuroblastoma genes by combining genomic and expression microarrays: expression data; GSE13137: Identification of candidate neuroblastoma genes by combining genomic and expression microarrays: SNP data Experiment Overall Design: Refer to individual Series
Project description:An appendix to the published Gaulton et al. work (PMID: 20118932; E-GEOD-17616). In the original paper, the authors note that samples 1 and 2 are not as pure as the third sample. This appendix provides FAIRE-Seq data obtained from a purified islet sample to replace the problematic published data. The goal of the original experiment was to identify active regulatory DNA in human pancreatic islets. This was accomplished using high-throughput sequencing of genomic regions isolated using FAIRE from three purified pancreatic islet samples to identify sites of open chromatin.