Project description:Transcription profiling by array of adipose samples from LDLR-/- mice to study response to anti-diabetic drug and dietary lifestyle interventions

| PRJNA247476 | ENA

Homo sapiens

Project description:HCT116 cells transcription array

| PRJNA486220 | ENA

Homo sapiens

Project description:HCT116 cells transcription array

| PRJNA486219 | ENA

Defining the effects of genetic variation on a proteome-wide scale

Project description:Genetic variation governs protein expression through both transcriptional and post-transcriptional processes. To investigate this relationship, we combined a multiplexed, mass spectrometry-based method for protein quantification with an emerging mouse model harboring extensive genetic variation from 8 founder strains. We collected genome-wide mRNA and protein profiling measurements to link genetic variation to protein expression differences in livers from 192 diversity outcross mice. We observed nearly 3,700 protein-level quantitative trait loci (pQTL) with an equal proportion of proteins regulated directly by their cognate mRNA as uncoupled from their transcript. Our analysis reveals an extensive array of at least five models for genetic variant control of protein abundance including direct protein-to-protein associations that act to achieve stoichiometric balance of functionally related enzymes and subunits of multimeric complexes.

2017-11-08 | MSV000081696 | MassIVE

Mus musculus

Project description:[E-MTAB-368] Transcription profiling by array of mouse embryos at 8 different stages

| PRJNA143267 | ENA

Gallus gallus

Project description:[E-MTAB-366] Transcription profiling by array of chicken embryos at 15 different stages

| PRJNA143263 | ENA