Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-GEOD-55356

ABSTRACT: p38a-dependent gene expression in the colonic mucosa

PROVIDER: E-GEOD-55356 | ExpressionAtlas | 2014-07-09

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-GEOD-55356-analysis-methods.tsv	Tabular
	E-GEOD-55356-atlasExperimentSummary.Rdata	Rdata
	E-GEOD-55356-configuration.xml	Xml
	E-GEOD-55356-percentile-ranks.tsv	Tabular
	E-GEOD-55356.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 54

Similar Datasets

Mus musculus

Project description:p38a-dependent gene expression in the colonic mucosa

| PRJNA239404 | ENA

p38a-dependent gene expression in the colonic mucosa

Project description:Gene expression in the colonic mucosa of wild-type and p38a-knockout intestinal epithelial cells (IECs) were compared. C57BL/6 wild-type mice, and intestinal epithelial cell-specific p38a-knockout mice on a C57BL/6 background were used for isolation of colonic mucosa

2014-07-01 | GSE55356 | GEO

p38a-dependent gene expression in the colonic mucosa

2014-07-01 | E-GEOD-55356 | biostudies-arrayexpress

Curcumin for the Chemoprevention of Colorectal Cancer

Project description:Specific Aims: * To determine if curcuminoids modulate cellular proliferation as measured by proliferating cell nuclear antigen (PCNA) in the colorectal mucosa of subjects with previously resected adenomatous colonic polyps. Hypothesis: Curcuminoids decrease cellular proliferation in the colorectal mucosa of subjects with previously resected sporadic adenomatous colonic polyps. * To determine if curcuminoids modulate apoptosis, as measured by TUNEL assay, in the colorectal mucosa of subjects with previously resected adenomatous colonic polyps. Hypothesis: Curcuminoids increase apoptosis in colorectal mucosa of subjects with previously resected sporadic adenomatous colonic polyps. * To determine if curcuminoids modulate COX-2 expression as measured by immunohistochemical assays in subjects with previously resected adenomatous colonic polyps Hypothesis: Curcuminoids decrease colorectal mucosa COX-2 expression in subjects with previously resected sporadic adenomatous colonic polyps. * To determine if curcuminoids modulate COX-2 activity as measured by urinary eicosanoids Hypothesis: Curcuminoids decrease concentrations of urinary eicosanoids.

| 2013415 | ecrin-mdr-crc

Genome-wide analysis of gene expression in partial Dnmt3a deleted colon mucosa cells of APC(Min/+) mice

Project description:Analysis of gene expression in partial Dnmt3a deleted colon mucosa cells of APC(Min/+) mice. In the present study the influence of Dnmt3a deletion on colonic tumorigenesis, gene expression and DNA methylation was analyzed. Results provide important information about the role of Dnmt3a in colonic tumorigenesis.

2015-06-01 | GSE48115 | GEO

Progastrin dependent cancer cell proliferation

Project description:Overexpression of human progastrin (hGAS) in mice has been observed to increase colonic mucosa proliferation significantly, but the mechanism and receptors of progastrin have not been defined. We investigated this mechanism by observing the microarray gene expression in mGAS-/- mice, WT mice, and hGAS transgenic mice. Gene expression of colonic mucosa of WT C57BL/6 mice,Gas-/- C57BL/6 mice, and hGAS transgenic mice, all 6 weeks old were compared.

2016-04-03 | E-GEOD-28620 | biostudies-arrayexpress

Genome-wide mRNA expression profiling for Wild Type and Itch-/- colonic mucosa Transcriptomes by RNA sequencing

Project description:To test the hypothesis that defects in the termination of inflammatory signaling led to colon inflammation, we isolated RNA from the colonic mucosa of Itch-/- mice and from the colonic mucosa of wild-type mice treated with DSS and performed genome-wide mRNA expression profiling by RNA sequencing.

2016-06-20 | GSE81066 | GEO

Transcription profiling of rat colonic mucosa at different time points following Salmonella infection

Project description:Salmonella enteritidis is suggested to translocate in the small intestine. Previously we identified that prebiotics, fermented in the colon, increased Salmonella translocation in rats, suggesting involvement of the colon in translocation. Effects of Salmonella on colonic gene expression in vivo are largely unknown. The aim of this study was to characterize time dependent Salmonella induced changes of colonic mucosal gene expression in rats using whole genome microarrays. Rats were orally infected with Salmonella enteritidis to mimic a foodbore infection and colonic gene expression was determined at day 1, 3 and 6 post-infection (n=8 per timepoint). Agilent rat whole genome microarray (G4131A Agilent Technologies) were used. Results indicate that colon is clearly a target tissue for Salmonella considering the abundant changes in mucosal gene expression observed. Keywords: Time point infection study, colon mucosa, Rat

2007-10-18 | GSE7496 | GEO

Alterations in gene expression due to aberrant DNA methylation are associated with the effects of anti-EGFR antibodies.

Project description:Gene expression profiles of nine paired samples collected from formalin-fixed and paraffin embedded primary tumor and normal colonic mucosa in the OCH paired cohort.

2022-04-22 | GSE185770 | GEO

Gene expression profiling of colorectal tissues in the early adenoma-carcinoma sequence

Project description:Colorectal cancer (CRC) is the third most common cancer worldwide. Colorectal polyps are recognised pre-cursors of CRC, however hyperplastic polyps lack malignant potential. The purpose of this study was to identify differences in gene expression between normal colonic mucosa, hyperplastic and adenomatous polyps from disease-free individuals. By comparing polyps believed to have malignant potential (adenomatous polyps) with hyperplastic polyps it is hoped that new insights into colorectal carcinogenesis can be achieved. 24 colonic samples comprising 8 normal colonic mucosa, 8 hyperplastic polyps and 8 adenomatous polyps.

2012-08-25 | E-GEOD-40362 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data