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E-MEXP-2238

ABSTRACT: Transcription profiling of mouse embryonic stem cell line CGR8 transfected with control shRNA and shRNA against HP1g in two different developmental stages

PROVIDER: E-MEXP-2238 | ExpressionAtlas | 2015-10-22

REPOSITORIES: ExpressionAtlas

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Dataset's files

Source:

			Action	DRS
	E-MEXP-2238-analysis-methods.tsv	Tabular
	E-MEXP-2238-atlasExperimentSummary.Rdata	Rdata
	E-MEXP-2238-configuration.xml	Xml
	E-MEXP-2238-percentile-ranks.tsv	Tabular
	E-MEXP-2238.condensed-sdrf.tsv	Tabular

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Transcription profiling of mouse embryonic stem cell line CGR8 transfected with control shRNA and shRNA against HP1g in two different developmental stages

Project description:The work was done one mouse embryonic stem cells. <br>Three independent experiments were carried out. <br>Two cell lines were used. They derive from the same cell line (CGR8). ShCTR is a cell line transduced with a control shRNA. ShN2 is a cell line transduced with a shRNA against HP1g. <br>The different stage of these cell lines were analysed : proliferating undifferentiated cells (ES) and differentiated cells (EB36h).<br>

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Loss of SOX2 expression induces cell migration via Vimentin up-regulation and serves as unfavourable risk factor for poor survival of head and neck squamous cell carcinoma patients

Project description:Transcriptional profiling of patient derived HNSCC (head and neck squamous cell carcinoma) cell line HNO223 comparing control cells transfected with shRNA against luciferase (shLuci) with cells transfected with two different shRNAs targeting SOX2. The goal was to determine the effects of SOX2 knockdown on global gene expression.

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