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Omics score: 3

Transcription profiling by array of rat kidney from animals with low, normal or high blood pressure

ABSTRACT: Hypertensive congenic kidney - 21 week Salt RAE230A and B

PROVIDER: E-MIMR-541 | ExpressionAtlas | 2014-08-16

REPOSITORIES: ExpressionAtlas

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Microarray analysis of rat chromosome 2 congenic strains.

McBride Martin W MW Carr Fiona J FJ Graham Delyth D Anderson Niall H NH Clark James S JS Lee Wai K WK Charchar Fadi J FJ Brosnan M Julia MJ Dominiczak Anna F AF

Hypertension (Dallas, Tex. : 1979) 20021202 3 Pt 2

Human essential hypertension is a complex polygenic trait with underlying genetic components that remain unknown. The stroke-prone spontaneously hypertensive rat (SHRSP) is a model of human essential hypertension, and a number of reproducible blood pressure regulation quantitative trait loci have been found to map to rat chromosome 2. The SP.WKYGla2c* congenic strain was produced by introgressing a region of rat chromosome 2 from the normotensive Wistar Kyoto (WKY) strain into the genetic backgr ...[more]

PMID: 12624007

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