Transcriptomics

Dataset Information

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Transcription profiling by RNA-seq of six African green monkey tissues at different ages (Chlorocebus aethiops sabaeus)


ABSTRACT: Characterization of transcriptomic variation is emerging as a critical tool for understanding how quantitative trait loci (QTL) contribute to complex phenotypes. Human transcriptomic studies are limited by factors such as the feasibility of invasive tissue collection or variable environmental exposures that can be readily overcome in non-human primate (NHP) models. We characterized transcriptomic variation across multiple tissues and developmental stages and between individuals in 59 vervet monkeys from the Vervet Research Colony extended pedigree. We conducted RNA sequencing across early (7, 90 days, and one year) and later (1.25, 1.5, 1.75, 2, 2.5, 3, and 4+ years old) developmental time points in 6 individuals at each stage in five tissue types: two brain tissues from hippocampus and caudate, two endocrine tissues (pituitary and adrenal) and two peripheral tissues serving as a source of biomarkers (blood and fibroblasts)

REANALYSIS of: E-MTAB-4404

ORGANISM(S): Chlorocebus sabaeus  

PROVIDER: E-MTAB-4404 | ExpressionAtlas | 2016-09-23

REPOSITORIES: ExpressionAtlas

Dataset's files

Source:
Action DRS
E-MTAB-4404-analysis-methods.tsv Tabular
E-MTAB-4404-atlasExperimentSummary.Rdata Rdata
E-MTAB-4404-coexpressions.tsv.gz Tabular
E-MTAB-4404-configuration.xml Xml
E-MTAB-4404-configuration.xml.beforeQC Xml
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