Dataset Information


Transcription profiling by array of human lymphocytes from prostate carcinoma patients after X-radiation treatment

ABSTRACT: For a case-control study, we selected 54 prostate carcinoma patients with no evidence of disease 2 years after curative


ORGANISM(S): Homo sapiens  

PROVIDER: E-TABM-90 | ExpressionAtlas | 2015-07-29

REPOSITORIES: ExpressionAtlas

altmetric image


Analysis of gene expression using gene sets discriminates cancer patients with and without late radiation toxicity.

Svensson J Peter JP   Stalpers Lukas J A LJ   Esveldt-van Lange Rebecca E E RE   Franken Nicolaas A P NA   Haveman Jaap J   Klein Binie B   Turesson Ingela I   Vrieling Harry H   Giphart-Gassler Micheline M  

PLoS medicine 20061001 10

BACKGROUND: Radiation is an effective anti-cancer therapy but leads to severe late radiation toxicity in 5%-10% of patients. Assuming that genetic susceptibility impacts this risk, we hypothesized that the cellular response of normal tissue to X-rays could discriminate patients with and without late radiation toxicity. METHODS AND FINDINGS: Prostate carcinoma patients without evidence of cancer 2 y after curative radiotherapy were recruited in the study. Blood samples of 21 patients with severe  ...[more]

Similar Datasets

2007-12-01 | E-TABM-90 | ArrayExpress
2007-08-01 | E-TABM-242 | ArrayExpress
2010-08-01 | E-TABM-904 | ArrayExpress
2011-09-30 | E-GEOD-30264 | ArrayExpress
2008-06-15 | E-GEOD-7398 | ArrayExpress
2010-06-01 | E-TABM-885 | ArrayExpress
2010-08-05 | E-GEOD-23419 | ArrayExpress
2013-12-01 | E-MEXP-3968 | ArrayExpress
2009-07-01 | E-MEXP-2037 | ArrayExpress
2018-10-24 | PXD006735 | Pride