Histopathology and Lo-multiplex immunofluorescence dataset of cell‐cycle related proteins in renal cell carcinoma – Scottish cohort
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ABSTRACT: This entry describes a retrospective cohort of clear-cell renal cell carcinoma (ccRCC) patients from Edinburgh (NHS Lothian). A total of 120 archival nephrectomy specimens from patients with no previous treatment were included. Digital whole-slide images are available for all 120 cases stained with haematoxylin and eosin (H&E) and for 88 cases stained using multiplex immunofluorescence (mIF). The mIF panel comprised p21^CDKN1A, MCM2, and Lamin B1, with Hoechst nuclear counterstain. All slides were scanned at 20× magnification using a Zeiss Axio Scan.Z1, generating high-resolution bright-field and fluorescence images in CZI format. The dataset includes the H&E and multi-channel mIF images, derived single-cell phenotype tables, and a de-identified clinical data file.
Image analysis was perfo
SUBMITTER: Hazem Abdullah
PROVIDER: S-BIAD2454 | bioimages |
REPOSITORIES: bioimages
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