Models

Dataset Information

0

Smolen2002_CircClock

ABSTRACT: This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2010 The BioModels Team.For more information see the terms of use.To cite BioModels Database, please use Le Novère N., Bornstein B., Broicher A., Courtot M., Donizelli M., Dharuri H., Li L., Sauro H., Schilstra M., Shapiro B., Snoep J.L., Hucka M. (2006) BioModels Database: A Free, Centralized Database of Curated, Published, Quantitative Kinetic Models of Biochemical and Cellular Systems Nucleic Acids Res., 34: D689-D691.

SUBMITTER: Nicolas Le Novère  

PROVIDER: BIOMD0000000025 | BioModels | 2005-06-29

REPOSITORIES: BioModels

Json Xml
altmetric image

Publications

A reduced model clarifies the role of feedback loops and time delays in the Drosophila circadian oscillator.

Smolen Paul P   Baxter Douglas A DA   Byrne John H JH  

Biophysical journal 20021101 5

Although several detailed models of molecular processes essential for circadian oscillations have been developed, their complexity makes intuitive understanding of the oscillation mechanism difficult. The goal of the present study was to reduce a previously developed, detailed model to a minimal representation of the transcriptional regulation essential for circadian rhythmicity in Drosophila. The reduced model contains only two differential equations, each with time delays. A negative feedback  ...[more]

PMID: 12414672

Publication: 1/2

Similar Datasets

Models Leloup1999_CircClock
2005-06-29 | BIOMD0000000021 | BioModels
Models Bray1995_chemotaxis_receptorlinkedcomplex
2008-11-07 | BIOMD0000000200 | BioModels
Models Birtwistle2007_ErbB_Signalling
2008-07-17 | BIOMD0000000175 | BioModels
Models Goldbeter1990_CalciumSpike_CICR
2007-03-21 | BIOMD0000000098 | BioModels
Models Blum2000_LHsecretion_1
2006-11-09 | BIOMD0000000077 | BioModels
Models Leloup2003_CircClock_DD_REV-ERBalpha
2006-10-19 | BIOMD0000000074 | BioModels
Models Meyer1991_CalciumSpike_ICC
2009-08-05 | BIOMD0000000224 | BioModels
Models Markevich2004_MAPK_AllRandomElementary
2005-05-26 | BIOMD0000000030 | BioModels
Models Izhikevich2004_SpikingNeurons_subthresholdOscillations
2007-07-16 | BIOMD0000000135 | BioModels
Models Izhikevich2004_SpikingNeurons_inhibitionInducedSpiking
2007-07-16 | BIOMD0000000129 | BioModels