ABSTRACT:
This is a model of the coupled Natch, Wnt and FGF modules as described in:
A. Goldbeter and O. Pourquié
, Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways.
J Theor Biol. 2008 Jun 7;252(3):574-85, pubmed ID: 18308339
To uncouple the modules remove the reaction MAx_trans_Xa
and set vsFK=vsF
.
The SBML version of the model was converted from the CellML version
by Catherine Lloyd for the CellML repository
.
To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication
for more information.
In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.
To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
Lukas Endler