Dataset Information
Noguchi2013 - Insulin dependent glucose metabolism
Ontology highlight
ABSTRACT:
DISEASE(S): Diabetes Mellitus
SUBMITTER: 
Rei Noguchi
PROVIDER: BIOMD0000000482 | BioModels | 2013-09-23
REPOSITORIES: BioModels
Publications
The selective control of glycolysis, gluconeogenesis and glycogenesis by temporal insulin patterns.
Molecular systems biology 20130514
Insulin governs systemic glucose metabolism, including glycolysis, gluconeogenesis and glycogenesis, through temporal change and absolute concentration. However, how insulin-signalling pathway selectively regulates glycolysis, gluconeogenesis and glycogenesis remains to be elucidated. To address this issue, we experimentally measured metabolites in glucose metabolism in response to insulin. Step stimulation of insulin induced transient response of glycolysis and glycogenesis, and sustained respo ...[more]
