Dataset Information
Philipson2015 - Innate immune response modulated by NLRX1
Ontology highlight
ABSTRACT:
DISEASE(S): Helicobacter Pylori Infectious Disease
SUBMITTER: 
Casandra Philipson
PROVIDER: BIOMD0000000596 | BioModels | 2019-07-25
REPOSITORIES: BioModels
Publications
Modeling the Regulatory Mechanisms by Which NLRX1 Modulates Innate Immune Responses to Helicobacter pylori Infection.
PloS one 20150914 9
Helicobacter pylori colonizes half of the world's population as the dominant member of the gastric microbiota resulting in a lifelong chronic infection. Host responses toward the bacterium can result in asymptomatic, pathogenic or even favorable health outcomes; however, mechanisms underlying the dual role of H. pylori as a commensal versus pathogenic organism are not well characterized. Recent evidence suggests mononuclear phagocytes are largely involved in shaping dominant immunity during infe ...[more]
