Ontology highlight
ABSTRACT:
SUBMITTER: Sarubini Kananathan
PROVIDER: BIOMD0000000711 | BioModels | 2018-10-16
REPOSITORIES: BioModels
Journal of theoretical biology 20061219 1
We present a simplified dynamical model of immune response to uncomplicated influenza A virus (IAV) infection, which focuses on the control of the infection by the innate and adaptive immunity. Innate immunity is represented by interferon-induced resistance to infection of respiratory epithelial cells and by removal of infected cells by effector cells (cytotoxic T-cells and natural killer cells). Adaptive immunity is represented by virus-specific antibodies. Similar in spirit to the recent model ...[more]