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Manchanda2014 - Effect on Immune System by 4 different Influenza A virus strains


ABSTRACT: No description

SUBMITTER: Sarubini Kananathan  

PROVIDER: BIOMD0000000712 | BioModels | 2018-10-16

REPOSITORIES: BioModels

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Publications

Within-host influenza dynamics: a small-scale mathematical modeling approach.

Manchanda Himanshu H   Seidel Nora N   Krumbholz Andi A   Sauerbrei Andreas A   Schmidtke Michaela M   Guthke Reinhard R  

Bio Systems 20140311


The emergence of new influenza viruses like the pandemic H1N1 influenza A virus in 2009 (A(H1N1)pdm09) with unpredictable difficulties in vaccine coverage and established antiviral treatment protocols emphasizes the need of new murine models to prove the activity of novel antiviral compounds in vivo. The aim of the present study was to develop a small-scale mathematical model based on easily attainable experimental data to explain differences in influenza kinetics induced by different virus stra  ...[more]

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