Dataset Information
Reynolds2006 - Reduced model of the acute inflammatory response
Ontology highlight
ABSTRACT:
SUBMITTER: 
Sarubini Kananathan
PROVIDER: BIOMD0000000714 | BioModels | 2018-10-17
REPOSITORIES: BioModels
Publications
A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation.
Journal of theoretical biology 20060403 1
The acute inflammatory response, triggered by a variety of biological or physical stresses on an organism, is a delicate system of checks and balances that, although aimed at promoting healing and restoring homeostasis, can result in undesired and occasionally lethal physiological responses. In this work, we derive a reduced conceptual model for the acute inflammatory response to infection, built up from consideration of direct interactions of fundamental effectors. We harness this model to expl ...[more]
