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Ota2015 - Positive regulation of Rho GTPase activity by RhoGDIs as a result of their direct interaction with GAPs (GDI integrated)


ABSTRACT: This is a ordinary differential equation mathematical model describing the Rho GTPase cycle in which Rho GDP-dissociation inhibitors (RhoGDIs) inhibit the regulatory activities of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs) by interacting with them directly as well as by sequestering the Rho GTPases. The model was constructed with the intent of analyzing the role of RhoGDIs in Rho GTPase signaling.

SUBMITTER: Johannes Meyer  

PROVIDER: BIOMD0000000899 | BioModels | 2019-12-17

REPOSITORIES: BioModels

Dataset's files

Source:
Action DRS
BIOMD0000000899?filename=Ota2015_GDI-integrated.cps Other
BIOMD0000000899?filename=Ota2015_GDI-integrated.sedml Other
BIOMD0000000899?filename=Ota2015_GDI-integrated.xml Xml
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