Ontology highlight
ABSTRACT:
SUBMITTER:
Adil Mardinoglu
PROVIDER: MODEL1402200002 | BioModels | 2005-01-01
REPOSITORIES: BioModels
Items per page: 1 - 5 of 8 |

Nature communications 20140101
Several liver disorders result from perturbations in the metabolism of hepatocytes, and their underlying mechanisms can be outlined through the use of genome-scale metabolic models (GEMs). Here we reconstruct a consensus GEM for hepatocytes, which we call iHepatocytes2322, that extends previous models by including an extensive description of lipid metabolism. We build iHepatocytes2322 using Human Metabolic Reaction 2.0 database and proteomics data in Human Protein Atlas, which experimentally val ...[more]