E2_PBPK

ABSTRACT: Using scaling from PhysB model Blood flow in L/hr Compartments in Kg Baseline as ~0.013nM free E2 in plasma_venous E2 biosynthesis rate constant = 2 E2 biosynthesis species = 1nM CLeh = 5 CLint = 1scaled by liver weight B:P = 0.286 IV bolus = 250/h (delivers in 2-3mins) Added ER{gonads}

SUBMITTER: Nick Plant  

PROVIDER: MODEL1711210001 | BioModels | 2018-02-02

REPOSITORIES: BioModels