WormJam-GEM
Ontology highlight
ABSTRACT:
SUBMITTER: 
Nicolas Rodriguez
PROVIDER: MODEL1807230002 | BioModels | 2018-12-10
REPOSITORIES: BioModels
Publications
Modeling Meets Metabolomics-The WormJam Consensus Model as Basis for Metabolic Studies in the Model Organism <i>Caenorhabditis elegans</i>.
Witting Michael M Hastings Janna J Rodriguez Nicolas N Joshi Chintan J CJ Hattwell Jake P N JPN Ebert Paul R PR van Weeghel Michel M Gao Arwen W AW Wakelam Michael J O MJO Houtkooper Riekelt H RH Mains Abraham A Le Novère Nicolas N Sadykoff Sean S Schroeder Frank F Lewis Nathan E NE Schirra Horst-Joachim HJ Kaleta Christoph C Casanueva Olivia O
Frontiers in molecular biosciences 20181114
Metabolism is one of the attributes of life and supplies energy and building blocks to organisms. Therefore, understanding metabolism is crucial for the understanding of complex biological phenomena. Despite having been in the focus of research for centuries, our picture of metabolism is still incomplete. Metabolomics, the systematic analysis of all small molecules in a biological system, aims to close this gap. In order to facilitate such investigations a blueprint of the metabolic network is r ...[more]
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This model is hosted on
BioModels Database
and identified by:
MODEL1604210000.
To cite BioModels Database, please use:
BioModels Database:
An enhanced, curated and annotated resource for published
quantitative kinetic models.
To the extent possible under law, all copyright and related or
neighbouring rights to this encoded model have been dedicated to
the public domain worldwide. Please refer to
CC0
Public Domain Dedication for more information.
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This model is hosted on
BioModels Database
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To cite BioModels Database, please use:
BioModels Database:
An enhanced, curated and annotated resource for published
quantitative kinetic models.
To the extent possible under law, all copyright and related or
neighbouring rights to this encoded model have been dedicated to
the public domain worldwide. Please refer to
CC0
Public Domain Dedication for more information.
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This model is one of the two versions
of ElegCyc presented in the paper. It describes the metabolism of a
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This model is described in the article:
A Genome-Scale Database and
Reconstruction of Caenorhabditis elegans Metabolism.
Gebauer J, Gentsch C, Mansfeld J,
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eukaryotes and mammals, including mice and humans. We
experimentally verify one of these peculiarities by showing
that the lifespan-extending effect of L-tryptophan
supplementation is dose dependent (hormetic). Finally, we show
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This model is hosted on
BioModels Database
and identified by:
MODEL1704200000.
To cite BioModels Database, please use:
BioModels Database:
An enhanced, curated and annotated resource for published
quantitative kinetic models.
To the extent possible under law, all copyright and related or
neighbouring rights to this encoded model have been dedicated to
the public domain worldwide. Please refer to
CC0
Public Domain Dedication for more information.
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