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Leung2016 - SIRWS model with immune boosting and cross-immunity between two pathogens


ABSTRACT: No description

SUBMITTER: Sarubini Kananathan  

PROVIDER: MODEL1808280006 | BioModels | 2018-09-06

REPOSITORIES: BioModels

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Publications

Periodic solutions in an SIRWS model with immune boosting and cross-immunity.

Leung Tiffany T   Hughes Barry D BD   Frascoli Federico F   McCaw James M JM  

Journal of theoretical biology 20160827


Incidence of whooping cough, an infection caused by Bordetella pertussis and Bordetella parapertussis, has been on the rise since the 1980s in many countries. Immunological interactions, such as immune boosting and cross-immunity between pathogens, have been hypothesised to be important drivers of epidemiological dynamics. We present a two-pathogen model of transmission which examines how immune boosting and cross-immunity can influence the timing and severity of epidemics. We use a combination  ...[more]

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