Dataset Information

Lavoie2020 - F.cylindrus_Genome_scale_model

ABSTRACT: This is an automatically generated .xml file describing a genome-scale model of the metabolism of a polar diatom, Fragilariopsis cylindrus. This reconstruction has been used for an in-depth study of metabolic robustness, which has been recently submitted for publication by Lavoie et al. (2020) in the journal Biology. The full MATLAB and Python 3 scripts associated with this scientific paper and this SBML model (as a .xml file) are available on the GitHub website (http://github.com/michellavoie4).

SUBMITTER: Michel Lavoie

PROVIDER: MODEL2001280001 | BioModels | 2021-01-18

REPOSITORIES: BioModels

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Publications

Genome-Scale Metabolic Reconstruction and in Silico Perturbation Analysis of the Polar Diatom Fragilariopsis cylindrus Predicts High Metabolic Robustness.

Lavoie Michel M Saint-Béat Blanche B Strauss Jan J Guérin Sébastien S Allard Antoine A V Hardy Simon S Falciatore Angela A Lavaud Johann J

Biology 20200217 2

Diatoms are major primary producers in polar environments where they can actively grow under extremely variable conditions. Integrative modeling using a genome-scale model (GSM) is a powerful approach to decipher the complex interactions between components of diatom metabolism and can provide insights into metabolic mechanisms underlying their evolutionary success in polar ecosystems. We developed the first GSM for a polar diatom, Fragilariopsis cylindrus, which enabled us to study its me ...[more]

PMID: 32079178

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Dataset Information

Lavoie2020 - F.cylindrus_Genome_scale_model

Publications

Genome-Scale Metabolic Reconstruction and <i>in Silico</i> Perturbation Analysis of the Polar Diatom <i>Fragilariopsis cylindrus</i> Predicts High Metabolic Robustness.

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