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Thomson2009 – Unlimited multistability in multisite phosphorylation systems


ABSTRACT: This model describes a distributive, sequential system with n = 4, which is a simplified example of unlimited multistability in multisite phosphorylation systems. This method can be applied to systems with multiple substrates and enzymes. This model is described in the article: Unlimited multistability in multisite phosphorylation systems. Thomson, Matthew & Gunawardena, Jeremy. (2009). Nature. 460. 274-7. 10.1038/nature08102 (https://www.nature.com/articles/nature08102). Antimony and Tellurium used. Figure 2 of the reference publication has been reproduced. The code files are available on Github (https://github.com/SunnyXu/Unlimited_multistability). The simulation was performed using Spyder for Tellurium 3.7 (http://tellurium.analogmachine.org/).

SUBMITTER: Jin Xu  

PROVIDER: MODEL2002110001 | BioModels | 2020-02-12

REPOSITORIES: BioModels

Dataset's files

Source:
Action DRS
MODEL2002110001?filename=Fig2-a.py Other
MODEL2002110001?filename=Fig2-b.py Other
MODEL2002110001?filename=Fig2a-1.pdf Pdf
MODEL2002110001?filename=Fig2a-2.pdf Pdf
MODEL2002110001?filename=Fig2b.pdf Pdf
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