Ontology highlight
ABSTRACT:
SUBMITTER:
Saugat Poudel
PROVIDER: MODEL2005290001 | BioModels | 2020-07-01
REPOSITORIES: BioModels
| Action | DRS | |||
|---|---|---|---|---|
| MODEL2005290001?filename=maltose_model.json | Other |
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Proceedings of the National Academy of Sciences of the United States of America 20200702 29
The ability of <i>Staphylococcus aureus</i> to infect many different tissue sites is enabled, in part, by its transcriptional regulatory network (TRN) that coordinates its gene expression to respond to different environments. We elucidated the organization and activity of this TRN by applying independent component analysis to a compendium of 108 RNA-sequencing expression profiles from two <i>S. aureus</i> clinical strains (TCH1516 and LAC). ICA decomposed the <i>S. aureus</i> transcriptome into ...[more]