Luna2013_CircadianClock_SIRT1

ABSTRACT: An in silico model to examine damage-induced circadian phase shifts by investigating a possible mechanism linking circadian rhythms to metabolism. The proposed model involves two DNA damage response proteins, SIRT1 and PARP1, that are each consumers of nicotinamide adenine dinucleotide (NAD), a metabolite involved in oxidation-reduction reactions and in ATP synthesis.

SUBMITTER: Augustin Luna  

PROVIDER: MODEL2112310002 | BioModels | 2021-12-31

REPOSITORIES: BioModels